Restores support to the deep tissue and improves skin quality in areas affected by volume loss.
Puresense 64 does not create volume: it stimulates the tissue to rebuild itself. Deposited in the hypodermis and the deep dermis, it activates the response of fibroblasts and adipocytes, re-establishing natural support where age, weight loss or laxity have reduced density and firmness.
Puresense 64 is not a volumising filler: it is linear hyaluronic acid at very high concentration — 64 mg/2 ml — not stabilised by BDDE. Its function is not structural, it is biological: to stimulate the endogenous production of collagen, elastin and HA.
Reactivates the hypodermic support of the deep cheekbone, restoring projection without adding exogenous volume.
Deposited in the temporal hypodermis, it reactivates the sub-fascial adipose tissue, reducing the skeletonised appearance.
Re-establishes tone and support along the jawline without creating focal volume: a qualitative upgrade of the tissue.
Reorganises the matrix in the areas where weight loss has reduced hypodermic density and skin firmness.
Grid-pattern stimulation on the mid-to-lower third: progressive improvement in elasticity, dermal thickness and radiance.
Biostimulation preparatory to structural treatments: it improves the quality of the tissue bed before injecting cross-linked gels.
Puresense 64 does not fill, it reactivates. It leaves no volumetric trace: it leaves tissue better than it found it.
The high concentration of linear HA stimulates the fibroblasts to synthesise type I and III collagen, elastin and endogenous hyaluronic acid over 4–8 weeks.
Complete physiological metabolisation in around 90 days. The gel disappears; the regenerated tissue remains. Optimal protocol: 3 sessions 30 days apart.
Non-cross-linked, non-stabilised, fully bio-identical HA. No BDDE residue, no need for enzymatic reversal.
Concentration, purity, origin: no parameter is left unexamined. Every choice answers to a required behaviour.
Deep fanning with a cannula across the cheekbone and temple. Dose of 0.3–0.5 ml per area, deposited slowly to stimulate the adipocyte response.
Point deposit in contact with the bone at zygomatic landmarks. Dose of 0.1–0.2 ml per point, for biostimulation of the sub-SMAS plane.
— Protocol guidance is intended for licensed healthcare professionals. Always consult the full instructions for use.
Puresense 64 works in the deep planes of the adipose tissue and within the supporting matrix. The improvement in skin quality visible at the surface is the result of the biological activation and structural reorganisation the product establishes in depth.

Superficial biorevitalisation, deep hydration and renewal of skin texture.

Tissue quality, deep hydration and superficial planes. Ideal before biostimulation.

Deep structural support. Cheekbones, nasal dorsum, jawline.